Eva Carro Selected Research

Low Density Lipoprotein Receptor-Related Protein-2

1/2020	Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge.
1/2017	Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin.
1/2015	Soluble Megalin is Reduced in Cerebrospinal Fluid Samples of Alzheimer's Disease Patients.
1/2014	Alzheimer's disease-like impaired cognition in endothelial-specific megalin-null mice.
11/2010	Megalin interacts with APP and the intracellular adapter protein FE65 in neurons.
6/2010	A megalin polymorphism associated with promoter activity and Alzheimer's disease risk.
6/2008	Megalin mediates the transport of leptin across the blood-CSF barrier.
11/2005	Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I.

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Eva Carro Research Topics

Disease

50	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2004
10	Cognitive Dysfunction 10/2020 - 07/2010
7	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2020 - 03/2004
6	Dementia (Dementias) 01/2021 - 01/2004
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 10/2009
5	Obesity 06/2020 - 06/2008
4	Neuroinflammatory Diseases 08/2021 - 01/2012
4	Inflammation (Inflammations) 01/2021 - 01/2012
3	Frontotemporal Dementia (Semantic Dementia) 01/2021 - 01/2017
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 09/2015
3	Amyloid Plaque 01/2020 - 01/2010
3	Amyloidosis 10/2009 - 04/2004
2	Parkinson Disease (Parkinson's Disease) 01/2018 - 04/2015
2	Brain Diseases (Brain Disorder) 01/2007 - 06/2006
1	Body Weight (Weight, Body) 01/2022
1	COVID-19 01/2022
1	Infections 01/2021
1	Disease Progression 10/2020
1	Neuroblastoma 01/2017
1	Proteostasis Deficiencies 01/2017
1	Schizophrenia (Dementia Praecox) 01/2016
1	Memory Disorders (Memory Loss) 09/2015
1	Hypertension (High Blood Pressure) 01/2010
1	Gliosis 11/2006
1	Cocaine-Related Disorders (Cocaine Addiction) 07/2005
1	Atrophy 04/2004

Drug/Important Bio-Agent (IBA)

19	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2004
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2006
8	Low Density Lipoprotein Receptor-Related Protein-2IBA 01/2020 - 11/2005
8	Insulin-Like Growth Factor I (IGF-1)IBA 03/2011 - 01/2004
7	Peptides (Polypeptides)IBA 10/2016 - 10/2009
6	LactoferrinIBA 01/2022 - 01/2017
6	Biomarkers (Surrogate Marker)IBA 08/2021 - 11/2010
5	Amyloid beta-PeptidesIBA 09/2013 - 10/2009
4	Insulin (Novolin)FDA Link 01/2022 - 04/2004
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2010
3	tau Proteins (tau Protein)IBA 01/2020 - 01/2010
3	LeptinIBA 01/2017 - 06/2008
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2015 - 01/2013
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2013 - 07/2010
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2020
2	LigandsIBA 01/2021 - 01/2014
2	Memantine (Namenda)FDA Link 06/2020 - 09/2018
2	CannabinoidsIBA 01/2018 - 01/2012
2	CytokinesIBA 01/2017 - 10/2016
2	LDL Receptors (LDL Receptor)IBA 01/2015 - 11/2010
2	GelsolinIBA 06/2010 - 10/2009
1	C-Reactive ProteinIBA 08/2021
1	Protein Kinases (Protein Kinase)IBA 01/2021
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2021
1	ElementsIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Annexin A5IBA 10/2020
1	Kynurenic Acid (Kynurenate)IBA 01/2020
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 01/2019
1	Guanosine Diphosphate (GDP)IBA 12/2018
1	VinculinIBA 12/2018
1	TalinIBA 12/2018
1	moesinIBA 12/2018
1	CalciumIBA 12/2018
1	Complement C3b (C3bi)IBA 12/2018
1	CREB-Binding ProteinIBA 06/2018
1	LipidsIBA 01/2018
1	IndazolesIBA 01/2018
1	CB2 Cannabinoid ReceptorIBA 01/2018
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2018
1	ButyrylcholinesteraseIBA 01/2018
1	Adenosine Monophosphate (AMP)IBA 01/2018
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 01/2018
1	Adenosine Diphosphate (ADP)IBA 01/2017
1	ATP Translocases Mitochondrial ADPIBA 01/2017
1	Valosin Containing ProteinIBA 01/2017
1	Adenosine Triphosphate (ATP)IBA 01/2017
1	AntibodiesIBA 10/2016
1	Chlorpromazine (Thorazine)FDA Link 01/2016
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 04/2015
1	Type 7 Cyclic Nucleotide PhosphodiesterasesIBA 09/2013
1	Presenilin-1IBA 09/2012
1	tacrine-8-hydroxyquinolineIBA 06/2012
1	Trace Elements (Biometals)IBA 06/2012
1	AcetylcholinesteraseIBA 06/2012
1	EnzymesIBA 06/2012
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2012
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2010
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 09/2010
1	Angiogenic ProteinsIBA 07/2010
1	Capsules (Microcapsules)IBA 07/2010
1	MelatoninIBA 05/2010
1	Tacrine (Cognex)FDA Link 05/2010
1	N(6)-carboxymethyllysine (carboxymethyllysine)IBA 10/2009
1	Lysine (L-Lysine)FDA Link 10/2009
1	Neuroprotective AgentsIBA 01/2007
1	IGF Type 1 Receptor (IGF 1 Receptor)IBA 11/2006
1	Cocaine (Cocaine HCl)IBA 07/2005

Therapy/Procedure

2	Therapeutics 01/2012 - 01/2004
1	Intranasal Administration 01/2018
1	Cell- and Tissue-Based Therapy (Cell Therapy) 08/2014
1	Craniotomy 08/2013
1	Nanospheres 08/2013